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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WHSC1 All Species: 18.79
Human Site: S583 Identified Species: 45.93
UniProt: O96028 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O96028 NP_001035889.1 1365 152258 S583 E A A S S L K S Q A A T K N L
Chimpanzee Pan troglodytes XP_001146084 1365 152240 S583 E A A S S L K S Q A A T K N L
Rhesus Macaque Macaca mulatta XP_001091062 1390 155951 L616 Q A T V K T G L Q K G A S E I
Dog Lupus familis XP_536224 1302 145396 S554 S S T P F S K S S S P S A S L
Cat Felis silvestris
Mouse Mus musculus Q8BVE8 1365 152234 S583 E A A S S L K S Q A A T K N L
Rat Rattus norvegicus XP_001058474 1365 152585 S583 E A A S S L K S Q A A T K N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516412 936 104874 V265 Q K H R D E V V A E H P D A S
Chicken Gallus gallus XP_420839 1369 154617 N588 E T S S S Q K N Q S A T K N L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001076020 1461 163773 S666 K C P K A A S S A P A A V P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT36 1427 159010 T607 R R K L S N G T E A D T G S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 43.5 87.9 N.A. 90.9 90.1 N.A. 55 80.3 N.A. 46.6 N.A. 26 N.A. N.A. N.A.
Protein Similarity: 100 99.8 59.3 90.9 N.A. 94.4 94.3 N.A. 60.4 88.3 N.A. 60.5 N.A. 43 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 20 N.A. 100 100 N.A. 0 66.6 N.A. 13.3 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 46.6 N.A. 100 100 N.A. 6.6 86.6 N.A. 26.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 40 0 10 10 0 0 20 50 60 20 10 10 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % D
% Glu: 50 0 0 0 0 10 0 0 10 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 20 0 0 0 10 0 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 10 10 10 10 10 0 60 0 0 10 0 0 50 0 0 % K
% Leu: 0 0 0 10 0 40 0 10 0 0 0 0 0 0 60 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 10 0 0 0 0 0 50 10 % N
% Pro: 0 0 10 10 0 0 0 0 0 10 10 10 0 10 0 % P
% Gln: 20 0 0 0 0 10 0 0 60 0 0 0 0 0 0 % Q
% Arg: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 50 60 10 10 60 10 20 0 10 10 20 10 % S
% Thr: 0 10 20 0 0 10 0 10 0 0 0 60 0 0 0 % T
% Val: 0 0 0 10 0 0 10 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _